June 8 status

Mapping progress by lab
  June 8 status
  No. of clones received since May 1 No. blots on hand (all five gels) No. of clones on hand still to map No. of mapped clones for which data are submitted No. of mapped clones for which data have not yet been submitted No. of mapped clones for which autorad image files have been submitted No. of unmappable clones (+reason) Mapping throughput (clones per week) Name of principal worker in charge of mapping Comment
J Anderson 36, 138 total 12 sets of 5, 40 by Aug 31 17 75 20 75 26: 14 high background; 12 elim by prev screening 12 due to supply, capacity for 20 to 40 J Gonzalez, full-time postdoc, with 2 ugrads No problems with inserts.
J Dubcovsky 85, 207 total 60 sets 82 49 0 28, 21 more to be submitted by June 15 72: most, 50, were from 1st plate produced under different selection conditions; remap attempts will be made on some. 20 is capacity, but with insert problems, average is lower Anura Ratanasiri, postdoc with assistance of 2 ugrads Replacement of DNAs has meant new blots are necessary, high cost in time and money for troubleshooting. Producing own inserts should improve mapability.
J Dvorak 36, 151 total 40 36 80 0 80 35, all high copy 20 is possible, but with recent insert problems, average since May 1 has been 3.3 Eduard Akhunov, postdoc with assistance of 2 ugrads. Continuing problem with inserts means need to re-amplify before hybridizing; would therefore rather get plasmids.
B Gill 96, 337 total 52 sets of five 42 225 53 196 20: 15 high copy, 5 weak signal 18 to 20    
K Gill 0, 110 total 50 sets of all five available, to have 64 sets by end of June 85 0 20 to be submittedbyn June 11 0 6, some smear pattern, so bands not clear 10, target is 20 Temp postdoc Lijia Ljiah, currently recruiting full-time postdoc Of the 110 clones, got only 25 as inserts and rest as plasmids; purifying inserts from plasmids is delay; prefer getting inserts.
P Gustafson 0, 73 total 11 sets of four blots with some blank lanes, 15 sets of five blots 36 5 10, to submit by 6/13 8 11 highly repetitive 10 Miftahudin, grad student, with assistance of ugrads. Had power failures, lost hyb oven, had to re-hyb.
S Kianian 0, 124 total 50 sets of all five 4, more efficient to have a set of 15, so waiting 35, had to rescore first set 59, to be submitted by 6/15 35 26: 6 empty wells, 4 high background, 16 didn't work, need again 30 to 40 K Hossain, half-time postdoc -- V Kalavacharla, half-time postodc -- J Hegstad, 20% technician Need about 50 clones per week, better is two full 96-well plates (i.e. total of 196) per month.
N Lapitan 0, 62 total 15 sets of 5 blots (4 blots in 7 sets have gone bad, leaving only 8 good sets); 11 sets of 4 blots (testing for quality; they appear to have lower DNA conc. than the 8 good sets) 45 0, last report indicated that 30 to 40 were expected to be submitted by this date. 17 0 4; 2 had strong background smear and weak bands; 1 was a repeated sequence with no bands; 1 had no missing bands in all the lines 8 (this is the no. of good complete sets we have on hand); target is 30. Junhua Peng, postdoc, with part-time assistance of postdoc Shifang, technician H. Zadeh, and ugrad D Arellano. Reorganized work assignments, current bottleneck is no. of blots, goal is to be up to 30 per week by July 15.
H Nguyen 24, 24 total 1 set of five, 10 sets by June 15 24 0 0 0 none known yet 20 by June 25 D Zhang, full-time postdoc, with 2 ugrads Had DNA digestion difficulties so blot preparation delayed.
M Sorrells 36, 167 total 60 sets of all five 22 52 76 52 17: high background and high copy Max 40, usually 30 C Bermudez, technician, whose last month is July, will need to hire and retrain in Aug/Sept Had to re-map a lot of the clones because the deletion line filters had to be made again after the workshop.

Last Updated on 6/19/2001
By Patrick E. McGuire