2005 Gordon Conference on "Quantitative Genetics and Genomics"
20 - 25 Feb 2005
Ventura, California



http://www.grc.org/05sched.htm


In planning the 2005 Gordon Conference on "Quantitative Genetics and
Genomics" we looked to expanding areas of science that are founded in
both classical quantitative genetics and evolution, and that are
advancing quickly due to the gain in information provided by genomics
and proteomics.  In the process of collecting session ideas and
speaker suggestions, it became abundantly clear that transcript
profiling has significantly impacted how we think about quantitative
variation and complex traits.  Transcript profiling (e.g., microarray
technology) is currently supporting the exploration of "genetic
architecture" (e.g., expression QTL mapping) and in turn has created
a great deal of excitement and interest across a variety of
organisms.  The molecular dissection of complex phenotypes is
providing direct evidence about gene regulation, evolution, the
genetic landscape, and the future roles of quantitative genetics.  It
is amazing how many people are thinking about related issues of
genetic architecture.  Therefore, our hope for this conference is to
provide a forum for the presentation of new ideas and data so that we
might all come away with a slightly stronger understanding of the
genetic basis of inheritance.


We look forward to meeting you in Ventura, CA in February of 2005!
Your continued participation and support of this conference is
greatly appreciated.  As you will see from the schedule, afternoons
are free for adventure and discussion, while poster sessions will be
held in the evening.


If you are a graduate student and would like to apply for the student
speaker competition (registration and travel included), please apply
to Rebecca Doerge (doerge@purdue.edu) by sending your CV, title,
abstract, and letter of recommendation from your advisor (e-mail is
fine). Deadline for travel fund application is December 1, 2004.
Successful applicants will be notified shortly thereafter.
If you would like to present a poster, please be sure to indicate
this on your Gordon Conference application.


Lastly, if you are interested in making a financial contribution to
the Chair's fund (to support registration, travel, and social
activities), please contact Rebecca Doerge (doerge@purdue.edu).


See you in Ventura!


Rebecca and  Patrick
Chair: R.W. Doerge (doerge@purdue.edu)
Co-Chair: Patrick Phillips (pphil@uoregon.edu)


Sunday
2:00 pm - 9:00 pm       Arrival and check-in
6:00 pm         Dinner

7:30 pm Welcome, Opening Remarks, & Announcements
                        Chair: Rebecca Doerge (Purdue University)

7:45 pm - 9:45 pm       At the Interface of Quantitative Genetics and Systems
                        Biology

Discussion Leader: Bruce Walsh (University of Arizona)

7:35 pm - 7:45 pm       Introduction and concepts (Bruce Walsh)

7:45 pm - 8:30 pm       Bruce Weir (North Carolina State Univerrsity)
'TBA'

8:30 pm - 8:45 pm       Discussion

8:45 pm - 9:30 pm       Eric Davidson (California Institute of Technology)
"The genomic regulatory system for embryonic development in the
sea urchin"

9:30 pm - 9:45 pm       Discussion


Monday
7:30 am - 8:30 am       Breakfast

9:00 am - 12:30 pm      Genetic Variation and Evolutionary Change
                        Discussion Leader: Patrick Phillips (University of
                         Oregon)
9:00 am - 9:10 am       Introduction and concepts (Patrick Phillips)

9:10 am - 9:40 am       Frédéric Hospital (INRA)
"The impact of selection on the apparent architecture of quantitative traits"

9:45 am - 10:15 am      Tom Osborn (University of Wisconsin, Madison)
"Genetic and epigenetic changes in newly formed polyploids"

10:20 am -10:40 am      Coffee Break

10:40 am - 11:10 am     Joanna Masel (University of Arizona)
"A population genetics framework to predict the evolution of evolutionary
capacitance"

11:15am         GROUP PHOTO

11:45 am - 12:15 pm     Sergey Nuzhdin (University of California, Davis)
"Functional analysis of expression variation: yeast and flies"

12:15 pm - 12:30 pm     Discussion

12:30 pm                Lunch

1:30 pm - 4:00 pm       Free Time

4:00 pm - 6:00 pm       Poster Viewing

6:00 pm         Dinner

7:30 pm - 9:30 pm       Mapping Genes Affecting Complex Traits in Humans
Discussion Leader: Zhao-Bang Zeng (North Carolina State University)

7:30 pm - 7:40pm        Introduction and concepts (Zhao-Bang Zeng)

7:40 pm - 8:25 pm       Heather Cordell (Cambridge Institute for
Medical Research)
"Detection and estimation of effects at interacting loci under
varying ascertainment schemes in genetic association studies"

8:30 pm - 9:15 pm       Lon Cardon (Wellcome Trust Centre for Human Genetics)
"Genome-wide linkage disequilibrium meets disease association"


9:15 pm - 9:30 pm       Discussion

9:30 pm         Posters and refreshments


Tuesday
7:30 am - 8:30 am       Breakfast

9:00 am - 12:30 pm      Genetic Architecture of Transcript Abundance Variation
                        Discussion Leader: Gary Churchill (Jackson
Laboratories)

9:00 am - 9:10 am       Introduction and concepts (Gary Churchill)

9:10 am - 9:40 am       Leonid Kruglyak/ Rachel Brem  (Fred
Hutchinson Cancer Research Center)
"The landscape of genetic complexity in the yeast transcriptome"

9:45 am - 10:00 am      Discussion

10:00 am - 10:30 am     Coffee Break

10:30 am - 11:00 am     Daniel Pomp (University of Nebraska, Lincoln)
                        "Genomic architecture of obesity predisposition"

11:05 am - 11:35 am     Rob Williams (University of Tennessee)
"Genetic network analysis of brain transcriptome, structure and function"

11:40 am - 12:10 pm     Peter Keightley (University of Edinburgh)
"Resolving genes that underlie quantitative variation for growth in mice"

12:15 pm - 12:30 pm     Discussion

12:30 pm                Lunch
1:30 pm - 4:00 pm       Free Time
4:00 pm - 6:00 pm       Poster Viewing
6:00 pm         Dinner

7:30 pm - 9:30 pm       So Much Diversity: Applied Genetics and
Genomics in Trees
        Discussion Leader:  TBA

7:30 pm - 7:40 pm       Introduction and concepts (TBA)

7:40 pm - 8:10 pm       Jeanne Romero-Severson (University of Notre Dame)
"Genetic maps in intractable species of forest trees"

8:15 pm - 8:45 pm       Dave Neale (University of California, Davis)
                        "Association genetics of natural genetic
diversity and complex traits in pine"

8:50 pm - 9:20 pm       Ron Sederoff (North Carolina State University)
                        "Transcript abundance variation in forest
trees and the molecular basis  of superior phenotypes"
9:20 pm - 9:30pm        Discussion
9:30 pm         Posters and refreshments


Wednesday
7:30 am - 8:30 am       Breakfast

9:00 am - 12:30 pm      Statistical Genetics and QTL Analysis

Discussion Leader: Rebecca Doerge  (Purdue University)

9:00 am - 9:10 am       Introduction and concepts (Rebecca Doerge)

9:10 am - 9:55 am       Örjan Carlborg (Uppsala University)
"Interactive genetics - Epistasis and the control of complex traits"

10:00 am - 10:30 am     Coffee Break

10:30 am - 11:15 am     Dina St. Clair (University of California, Davis)
"Quantitative traits in plants: QTL architecture, interactions, and dissection"

11:20 am - 12:05 pm     Peter Visscher (University of Edinburgh)
"Estimation of past effective population size from linkage
disequilibrium   between genetic markers"

12:10 pm - 12:30 pm     Discussion

12:30 pm                Lunch

1:30 pm - 4:00 pm       Free Time

4:00 pm - 6:00 pm       Poster Session
6:00 pm         Dinner

7:30 pm - 9:30 pm       Genomics of Polyploids and Student Presentations

Discussion Leader: Rob Martienssen (Cold Spring Harbor Labs)

7:30 pm - 8:15pm        Student Speaker (Affiliation)
'TBA'

8:20 pm - 8:50pm        BUSINESS MEETING

8:50pm - 9:20 pm        Shane Burgess (Mississippi State University)
"Livestock proteomics: challenges of GOing from MuDPITs"

9:20 pm - 9:30 pm       Discussion

9:30 pm         Posters and refreshments


Thursday
7:30 am - 8:30 am       Breakfast

9:00 am - 12:30 pm      Inference of Evolutionary History
Discussion Leader: Bill Beavis (National Center for Genome Resources)

9:00 am - 9:10 am       Introduction and concepts (Bill Beavis)

9:10 am - 9:55 am       Michael Purugganan (North Carolina State University)
"Evolutionary genetics of plant adaptation"

10:00 am  - 10:30 am    Coffee Break

10:30 am - 11:15 am     Laura Salter (University of New Mexico)
"Prospects and pitfalls of whole-genome phylogeny based on DNA   sequences"

11:20 am - 12:05 pm     Thomas Mitchell-Olds (Max Planck Institute
for Chemical Ecology)
"Evolutionary significance of ecologically important variation in
Arabidopsis relatives"

12:10 pm - 12:30 pm     Discussion

12:30 pm                Lunch

1:30 pm - 4:00 pm       Free Time

4:00 pm - 6:00 pm       Poster Viewing

6:00 pm         Dinner

7:30 pm - 9:30 pm       False Discovery Rate (FDR) for Genetic and
Genomic Data Discussion Leader: Sandrine Dudoit  (University of
California, Berkeley)


7:30 pm - 7:40 pm       Introduction and concepts (Sandrine Dudoit)

7:40 pm - 8:25 pm       John Storey (University of Washington)
"Statistical significance for multiple locus linkage analysis of
genome-wide expression"

8:30 pm - 9:15 pm       Yoav Benjamini (Tel Aviv University)
"Multiplicity issues in Statistical Genetics: QTL analysis, microarrays,
and behavior genetics"

9:15 pm - 9:30pm        Discussion

9:30 pm         Posters and refreshments


Friday
7:30 am - 8:30 am       Breakfast

9:00 am         Departure