PKC inhibitor from Roche.
Prepared in DMSO as a 5-10mM stock stored for months at -20¡C.
Effective concentration 3-10uM with 3uM being about an IC80
Derved from the structure of staurosporin, which is extremely effective (nM) but has low specificity. Ro 31.8220 has a high degree of specificity, blocking phorbol ester response but not forskolin response in cells.