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GrainGenes Reference Report: SCI-2020-Wang

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Reference
SCI-2020-Wang
Title
Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat
Journal
Science
Year
2020
Volume
09Apr2020
Author
Wang H
[ Show all 42 ]
Abstract
Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce food toxins, currently devastates wheat production worldwide, yet few resistance resources have been discovered in wheat germplasm. Here, we cloned the FHB resistance gene Fhb7 based on assembling the genome of Thinopyrum elongatum, a species used in wheat distant hybridization breeding. Fhb7 encodes a glutathione S-transferase (GST) and confers broad resistance to Fusarium species by detoxifying trichothecenes via de-epoxidation. Fhb7 GST homologs are absent in plants, and our evidence supports Th. elongatum has gained Fhb7 via horizontal gene transfer (HGT) from an endophytic Epichloe species. Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse wheat backgrounds without yield penalty, providing a solution for Fusarium resistance breeding.
External Databases
https://doi.org/10.1126/science.aba5435
Gene
Fhb7 (Triticum)
Locus
Tel7E01T1020600.1
[ Show all 24 ]
Map Data
Wheat_Fhb7_2020
Probe
SDAUK130
[ Show all 24 ]

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